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C6 L-threo Ceramide (d18:1/6:0)

Names

[ CAS No. ]:
189894-80-2

[ Name ]:
C6 L-threo Ceramide (d18:1/6:0)

[Synonym ]:
C6 L-threo Ceramide (d18:1/6:0)
N-[(2S,3S,4E)-1,3-Dihydroxy-4-octadecen-2-yl]hexanamide
Hexanamide, N-[(1S,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-

Biological Activity

[Description]:

C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides[1]. C6 L-threo Ceramide significantly inhibits IL-4 production in T cells. Anti-allergic agents[2].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Interleukin Related
Research Areas >> Inflammation/Immunology

[References]

[1]. Jin Park, et al. Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells. Bioorg Med Chem. 2005 Apr 1;13(7):2589-95.

[2]. Jin Park, et al. Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells. Bioorg Med Chem. 2005 Apr 1;13(7):2589-95.

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
574.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H47NO3

[ Molecular Weight ]:
397.635

[ Flash Point ]:
301.4±30.1 °C

[ Exact Mass ]:
397.355591

[ LogP ]:
8.02

[ Vapour Pressure ]:
0.0±3.6 mmHg at 25°C

[ Index of Refraction ]:
1.483

Related Compounds