(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester

Names

[ CAS No. ]:
1900-29-4

[ Name ]:
(-)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester

[Synonym ]:
Trypacidin

Biological Activity

[Description]:

Trypacidin is the conidia-bound metabolite with antiprotozoal activity. Trypacidin has a protective function against phagocytes both in the environment and during the infection process[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Mattern DJ, et al. Identification of the antiphagocytic trypacidin gene cluster in the human-pathogenic fungus Aspergillus fumigatus. Appl Microbiol Biotechnol. 2015;99(23):10151-10161.

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
582.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₆O₇

[ Molecular Weight ]:
344.31500

[ Flash Point ]:
258.4ºC

[ Exact Mass ]:
344.09000

[ PSA ]:
88.13000

[ LogP ]:
1.52990

[ Vapour Pressure ]:
1.53E-13mmHg at 25°C

[ Index of Refraction ]:
1.594