Adenylosuccinic acid
Names
[ CAS No. ]:
19046-78-7
[ Name ]:
Adenylosuccinic acid
[Synonym ]:
ADENYLOSUCCINIC ACID
N(6)-(1,2-dicarboxyethyl)-AMP
Aspartyl-AMP
adenylosuccnic acid
L-Aspartic acid 4-(5'-adenylyl) ester
Adenylobernsteinsaeure(L-)
Adenylsuccinic acid
aspartyl adenylate
N6-(1,2-dicarboxy-ethyl)-[5']adenylic acid
adenylosuccinic acid free acid
Biological Activity
[Description]:
[Related Catalog]:
[Target]
IC50: ribonucleoside monophosphate[1]
[In Vivo]
[References]
Chemical & Physical Properties
[ Density]:
2.19g/cm3
[ Boiling Point ]:
921.9ºC at 760mmHg
[ Molecular Formula ]:
C14H18N5O11P
[ Molecular Weight ]:
463.29300
[ Flash Point ]:
511.3ºC
[ Exact Mass ]:
463.07400
[ PSA ]:
256.49000
[ Vapour Pressure ]:
0mmHg at 25°C
[ Index of Refraction ]:
1.833
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
J. Bacteriol. 196(19) , 3377-85, (2014)
Peptide-nucleotide antibiotic microcin C (McC) is produced by some Escherichia coli strains. Inside a sensitive cell, McC is processed, releasing a nonhydrolyzable analog of aspartyl-adenylate, which ...
Synthesis and aminoacyl-tRNA synthetase inhibitory activity of aspartyl adenylate analogs.Bioorg. Med. Chem. 13(1) , 69-75, (2005)
Three nonhydrolyzable aspartyl adenylate analogs have been prepared and tested as inhibitors of E. coli aspartyl-tRNA synthetase. 5'-O-[N-(L-Aspartyl)sulfamoyl]adenosine is a potent competitive inhibi...
MccE provides resistance to protein synthesis inhibitor microcin C by acetylating the processed form of the antibiotic.J. Biol. Chem. 285(17) , 12662-9, (2010)
The heptapeptide-nucleotide microcin C (McC) is a potent inhibitor of enteric bacteria growth. McC is excreted from producing cells by the MccC transporter. The residual McC that remains in the produc...