5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid monohydrate

Names

[ CAS No. ]:
190908-40-8

[ Name ]:
5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid monohydrate

[Synonym ]:
5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid monohydrate
5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid,hydrate

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₇Cl₂NO₄

[ Molecular Weight ]:
276.07300

[ Exact Mass ]:
274.97500

[ PSA ]:
79.39000

[ LogP ]:
2.46880

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

Articles

[3H]5,7-dichlorokynurenic acid, a novel radioligand labels NMDA receptor-associated glycine binding sites.

Eur. J. Pharmacol. 206 , 149, (1991)

A strychnine-insensitive glycine binding site is located on the N-methyl-D-aspartate (NMDA)-preferring glutamate receptor complex. Kynurenic acid analogs are antagonists at this binding site. A deriva...

Activity of 5,7-dichlorokynurenic acid, a potent antagonist at the N-methyl-D-aspartate receptor-associated glycine binding site.

Mol. Pharmacol. 38 , 554, (1990)

5,7-Dichlorokynurenic acid (5,7-DCKA), one of the most potent excitatory amino acid receptor antagonists yet described, binds to a strychnine-insensitive glycine binding site located on the N-methyl-D...