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TACE substrate (fluorogenic)

Names

[ CAS No. ]:
192723-42-5

[ Name ]:
TACE substrate (fluorogenic)

[Synonym ]:
1-[(7-Methoxy-2-oxo-2H-chromen-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-glutaminyl-L-alanyl-L-valyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-arginyl-L-seryl-L-seryl-L-seryl-L-argininamide
L-Argininamide, 1-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-prolyl-L-leucyl-L-alanyl-L-glutaminyl-L-alanyl-L-valyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-arginyl-L-seryl-L-seryl-L-seryl-

Biological Activity

[Description]:

Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide. Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a fluorescence resonance energy transfer based substrate, the activity is measured by fluorescence intensity change upon cleavage[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Yi Wang, et al. Protease assay method using site-specific fluorescence dye labeled protein as substrate. US9708638. 2017.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C69H103N23O24

[ Molecular Weight ]:
1638.696

[ Exact Mass ]:
1637.754639

[ LogP ]:
-2.78

[ Index of Refraction ]:
1.683

[ Storage condition ]:
-15°C

Related Compounds