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Nor-benzetimide

Names

[ CAS No. ]:
19315-71-0

[ Name ]:
Nor-benzetimide

[Synonym ]:
3-phenyl-octahydro-[3,4']bipyridinyl-2,6-dione
3-phenyl-[3,4'-bipiperidine]-2,6-dione
4-(3-Phenyl-2,6-dioxo-3-piperidyl)-piperidin
3-Phenyl-[3,4']bipiperidinyl-2,6-dione

Biological Activity

[Description]:

Nor-benzetimide is a major metabolite of Benzetimide. Benzetimide is a mAChR antagonist with anticholinergic activity[1][2].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> mAChR
Signaling Pathways >> GPCR/G Protein >> mAChR
Research Areas >> Neurological Disease

[References]

[1]. I van Wijngaarden. Differential anticholinergic activity, metabolism and excretion of the optical isomers of 14C-benzetimide hydrochloride. Life Sci. 1969 May 1;8(9):517-23.

[2]. J A Gray, et al. Stereoselective binding in cardiac tissue of the enatiomers of benzetimide, and antimuscarinic drug. Br J Pharmacol. 1976 Apr;56(4):485-90.

Chemical & Physical Properties

[ Molecular Formula ]:
C16H20N2O2

[ Molecular Weight ]:
272.34200

[ Exact Mass ]:
272.15200

[ PSA ]:
58.20000

[ LogP ]:
2.01820

Related Compounds