5’-Azido-5’-deoxy-2’-O-methyluridine

Names

[ CAS No. ]:
194034-68-9

[ Name ]:
5’-Azido-5’-deoxy-2’-O-methyluridine

[Synonym ]:
Uridine,5'-azido-5'-deoxy-2'-O-methyl

Biological Activity

[Description]:

5’-Azido-5’-deoxy-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C9H11N5O5

[ Molecular Weight ]:
269.21

[ Exact Mass ]:
283.09200

[ PSA ]:
143.56000

Related Compounds