Curcumenol

Names

[ CAS No. ]:
19431-84-6

[ Name ]:
Curcumenol

[Synonym ]:
(1S,2S,5S,8R)-9-Isopropylidene-2,6-dimethyl-11-oxatricyclo[6.2.1.0]undec-6-en-8-ol
(3S,3aS,6R,8aS)-1,2,3,4,5,8a-hexahydro-3,8-dimethyl-5-(1-methylethylidene)-6H-3a,6-epoxyazulen-6-ol
(3S,3aS,8aS)-3,8-dimethyl-5-(propan-2-ylidene)-1,2,3,4,5,8a-hexahydro-6H-3a,6-epoxyazulen-6-ol
(3S,3aS,6R,8aS)-3,8-dimethyl-5-(propan-2-ylidene)-1,2,3,4,5,8a-hexahydro-6H-3a,6-epoxyazulen-6-ol
Curcumenol
(1S,2S,5S,8R)-9-isopropylidene-2,6-dimethyl-11-oxatricyclo[6.2.1.01,5]undec-6-en-8-ol
3,8-dimethyl-5-(1-methylethylidene)-,(3S,3aS,6R,8aS)
6H-3a,6-Epoxyazulen-6-ol, 1,2,3,4,5,8a-hexahydro-3,8-dimethyl-5-(1-methylethylidene)-, (3S,3aS,6R,8aS)-
(3S,3alphaS,6R,8alphaS)-1,2,3,4,5,8alpha-Hexahydro-3,8-dimethyl-5-(1-methylethylidene)-6H-3alpha,6-epoxyazulen-6-ol
6H-3a,6-Epoxyazulen-6-ol,1,2,3,4,5,8a-hexahydro

Biological Activity

[Description]:

Curcumenol is one of constituents in the plants of medicinally important genus of Curcuma[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[References]

[1]. Hamdi OA, et al. Spectrofluorometric and Molecular Docking Studies on the Binding of Curcumenol and Curcumenone to Human Serum Albumin. Int J Mol Sci. 2015 Mar 6;16(3):5180-93.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
349.3±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₂O₂

[ Molecular Weight ]:
234.33

[ Flash Point ]:
146.7±22.1 °C

[ Exact Mass ]:
234.161987

[ PSA ]:
29.46000

[ LogP ]:
3.40

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.553

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KC5020000

CHEMICAL NAME :: 6H-3a,6-Epoxyazulen-6-ol, 1,2,3,4,5,8a-hexahydro-3,8-dimethyl-5-(1-methylethyli dene)-, (3S-(3-alpha,3a-alpha,6-alpha,8a-beta))-

CAS REGISTRY NUMBER :: 19431-84-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H22-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85PEAG "Zhongliu Yanjiu" Cancer Review, Yu, R., et al., eds., Shanghai Science/Technology Publisher, Peop. Rep. China, 1994 Volume(issue)/page/year: -,178,1994

Curcumenol

Names

Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds