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Propargyl-PEG6-acid

Names

[ CAS No. ]:
1951438-84-8

[ Name ]:
Propargyl-PEG6-acid

[Synonym ]:
4,7,10,13,16,19-Hexaoxadocos-21-yn-1-oic acid
MFCD28950778

Biological Activity

[Description]:

Propargyl-PEG6-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Anandan Palani, et al. Insulin-incretin conjugates. WO2017160669A1.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
462.8±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H28O8

[ Molecular Weight ]:
348.389

[ Flash Point ]:
157.6±22.2 °C

[ Exact Mass ]:
348.178406

[ LogP ]:
-1.52

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.469


Related Compounds