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SB 258719

Names

[ CAS No. ]:
195199-95-2

[ Name ]:
SB 258719

[Synonym ]:
sb-258,719
SB 258719

Biological Activity

[Description]:

SB 258719 is a selective 5-HT7 receptor antagonist with a pKi of 7.5.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor
Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
Research Areas >> Neurological Disease

[Target]

pKi: 7.5 (5-HT7 receptor)


[References]

[1]. Thomas DR, et al. Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719. Br J Pharmacol. 1998 Jul;124(6):1300-6.


[Related Small Molecules]

Harmine | Pimavanserin | Serotonin hydrochloride | Sodium Ferulate | Thioridazine hydrochloride | Brexpiprazole | Risperidone | TG6-10-1 | Cariprazine | Quetiapine | SERTINDOLE | Alprenolol hydrochloride | B-HT 920 | Ketanserin | Palonosetron hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C18H30N2O2S

[ Molecular Weight ]:
338.51

[ PSA ]:
49.00000

[ LogP ]:
4.94670

[ Storage condition ]:
2-8℃

Related Compounds