2-amino-4-(S-methylsulphonimidoyl)butyric acid
Names
[ CAS No. ]:
1982-67-8
[ Name ]:
2-amino-4-(S-methylsulphonimidoyl)butyric acid
[Synonym ]:
methionine sulphoximine
methioninesulfoximine
Methioninsulfoximin
Methionin-S-imid-S-oxid
DL-METHIONINE SULFOXIMINE
L-METHIONINE-RS-SULPHOXIMINE
dl-methionine-dl-sulfoximin
DL-METHIONINE DL-SULFOXIMINE
DL-(3-Amino-3-carboxypropyl) methyl sulfoximine
CNESTINE
dl-sulfoximin
AURORA KA-705
METHIONINESULPHOXIME
methionine S-imide-S-oxide
DL-LOBAMINE-DL-SULFOXIMINE
Chemical & Physical Properties
[ Density]:
1.46g/cm3
[ Boiling Point ]:
352.2ºC at 760mmHg
[ Molecular Formula ]:
C5H12N2O3S
[ Molecular Weight ]:
180.22500
[ Flash Point ]:
166.8ºC
[ Exact Mass ]:
180.05700
[ PSA ]:
112.62000
[ LogP ]:
1.13070
[ Vapour Pressure ]:
6.63E-06mmHg at 25°C
[ Index of Refraction ]:
1.559
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WS3560000
- CHEMICAL NAME :
- Sulfoximine, S-(3-amino-3-carboxypropyl)-S-methyl-, DL-
- CAS REGISTRY NUMBER :
- 1982-67-8
- LAST UPDATED :
- 199206
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C5-H12-N2-O3-S
- MOLECULAR WEIGHT :
- 180.25
- WISWESSER LINE NOTATION :
- QVYZ2S1&UM -DL
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 218 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 94,12,1957
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03652 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 350 mg/kg
- SEX/DURATION :
- female 9-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - eye/ear
- REFERENCE :
- ASMUAA Acta Scholae Medicinalis Universitatis in Kioto. (Kyoto, Japan) V.27-40, 1947-70. Discontinued. Volume(issue)/page/year: 38,193,1962
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 3500 mg/kg
- SEX/DURATION :
- female 9-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- ASMUAA Acta Scholae Medicinalis Universitatis in Kioto. (Kyoto, Japan) V.27-40, 1947-70. Discontinued. Volume(issue)/page/year: 38,193,1962
Safety Information
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
36/37/38
[ WGK Germany ]:
3
[ RTECS ]:
WS3560000
[ HS Code ]:
2925290090
Customs
[ HS Code ]: 2925290090
[ Summary ]:
2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%