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CN-SAH

Names

[ CAS No. ]:
1985669-27-9

[ Name ]:
CN-SAH

Biological Activity

[Description]:

CN-SAH is a potent and selective inhibitor of histone methyl transferase DOT1L with IC50 of 26 nM, displays >10-fold selectivity over DNMT1, PRMT3, PRMT5, and G9α.

[References]

References 1. Spurr SS, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4518-22. View Related Products by Target Histone Methyltransferase (HMTase)

Chemical & Physical Properties

[ Molecular Formula ]:
C16H20N6O5S

[ Molecular Weight ]:
408.433


Related Compounds