H-D-Phg-OMe．HCl

Names

[ CAS No. ]:
19883-41-1

[ Name ]:
H-D-Phg-OMe．HCl

[Synonym ]:
(S)-2-PHENYLGLYCINE METHYL ESTER HYDROCHLORIDE
methyl (2S)-amino(phenyl)ethanoate hydrochloride (1:1)
D-phenylglycine methyl ester hydrochloride
Benzeneacetic acid, α-amino-, methyl ester, (αR)-, hydrochloride (1:1)
METHYL (2R)-2-AMINO-2-PHENYLACETATE HYDROCHLORIDE
EINECS 243-399-9
H-PH-Phg-Ome hydrochloride
S)-(+)-2-Phenylglycine methyl ester hydrochloride
D-Phenylycine Methyl Ester Hydrichloride
H-D-PHG-OME HCL
(R)-PGME hydrochloride
L-Phenylglycine methyl ester hydrochloride
Benzeneacetic acid, α-amino-, methyl ester, (αS)-, hydrochloride (1:1)
H-D-Phg-OMe.HCl
(S)-Methyl 2-amino-2-phenylacetate hydrochloride
H-PHG-OME HCL
(R)-Methyl 2-amino-2-phenylacetate hydrochloride
(S)-a-Amino-benzeneacetic acid methyl ester HCl
D-Phg-OMe*HCl
Methyl (2S)-amino(phenyl)acetate hydrochloride (1:1)
D-phenylglycine methyl ester ·HCl
L-Phenylglycine methylester hydrochloride
Methyl (2R)-amino(phenyl)acetate hydrochloride (1:1)
(R)-(-)-2-Phenylglycine Methyl Ester Hydrochloride
(R)-(−)-2-Phenylglycine methyl ester hydrochloride
(S)-(+)-2-Phenylglycine methyl ester hydrochloride
MFCD00137487
H-D-Phg-OMe．HCl

Biological Activity

[Description]:

H-D-Phg-OMe.HCl is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.126g/cm3

[ Boiling Point ]:
238.9ºC at 760mmHg

[ Melting Point ]:
189-191 °C(lit.)

[ Molecular Formula ]:
C₉H₁₂ClNO₂

[ Molecular Weight ]:
201.650

[ Flash Point ]:
104.7ºC

[ Exact Mass ]:
201.055649

[ PSA ]:
52.32000

[ LogP ]:
2.36170

[ Vapour Pressure ]:
0.0412mmHg at 25°C

[ Storage condition ]:
2~8°C

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Improving lipase-catalyzed enantioselective ammonolysis of phenylglycine methyl ester in organic solvent by in situ racemization.

Biotechnol. Lett. 25(6) , 461-4, (2003)

Lipase-catalyzed enantioselective ammonolysis of phenylglycine methyl ester was processed by in situ racemization with ammonium carbamate as the acyl acceptor. Using 1 mM benzaldehyde or 0.6 mM chloro...

Lipase-catalysed enantioselective ammonolysis of phenylglycine methyl ester in organic solvent.

Biotechnol. Appl. Biochem. 38(Pt 2) , 107-10, (2003)

Ammonium, provided by ammonium carbamate as a novel acyl acceptor, was adopted for enzymic enantioselective ammonolysis of racemic phenylglycine methyl ester in this paper and it has been found that t...

Kinetics of ampicillin synthesis catalyzed by penicillin acylase from E. coli in homogeneous and heterogeneous systems. Quantitative characterization of nucleophile reactivity and mathematical modeling of the process.

Biochemistry. (Mosc.) 65(12) , 1367-75, (2000)

Kinetic regularities of the enzymatic acyl group transfer reactions have been studied using ampicillin synthesis catalyzed by E. coli penicillin acylase as an example. It was shown that ampicillin syn...