5(6)-Carboxy-X-rhodamine

Names

[ CAS No. ]:
198978-94-8

[ Name ]:
5(6)-Carboxy-X-rhodamine

[Synonym ]:
3-Oxo-2',3',6',7',12',13',16',17'-octahydro-1'H,3H,5'H,11'H,15'H-spiro[2-benzofuran-1,9'-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinoline]-5-carboxylic acid - 3-oxo-2',3',6',7',12',13',16',17'-octahydro-1'H,3H,5'H,11'H,15'H-spiro[2-benzofuran-1,9'-pyrido[3,2,1-ij]quinolizino[1',9':6,7,8]chromeno[2,3-f]quinoline]-6-carboxylic acid (1:1)
Spiro[isobenzofuran-1(3H),9'-[1H,5H,9H,11H,15H]xantheno[2,3,4-ij:5,6,7-i'j']diquinolizine]-5-carboxylic acid, 2',3',6',7',12',13',16',17'-octahydro-3-oxo-, compd. with 2',3',6',7',12',13',16',17'-octahydro-3-oxospiro[isobenzofuran-1(3H),9'-[1H,5H,9H,11H,15H]xantheno[2,3,4-ij:5,6,7-i'j']diquinolizine]-6-carboxylic acid (1:1)
5(6)-ROX

Biological Activity

[Description]:

5(6)-ROX is a nucleic acid fluorescent label which can be used as a reference dye for real-time polymerase chain reaction.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

[References]

[1]. Wang G, et al. Optimization of 6-carboxy-X-rhodamine concentration for real-time polymerase chain reaction using molecular beacon chemistry. Can J Microbiol. 2007 Mar;53(3):391-7.

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₃H₃₀N₂O₅

[ Molecular Weight ]:
534.60

[ PSA ]:
158.62000

[ LogP ]:
10.96080

[ Storage condition ]:
20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Articles

High-resolution liquid chromatography of fluorescent dye-labeled nucleic acids.

Anal. Biochem. 223 , 39, (1994)

Using 100 mM of triethylammonium acetate as ion-pairing reagent, phosphodiester oligonucleotides labeled fluorescently at their 5' terminus could be separated successfully on alkylated nonporous 2.3-m...

Quantifying EGFR alterations in the lung cancer genome with nanofluidic digital PCR arrays.

Clin. Chem. 56 , 623-632, (2010)

The EGFR [epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)] gene is known to harbor genomic alterations in advanced lung cancer involving gene amplifi...

Four-color DNA sequencing by synthesis on a chip using photocleavable fluorescent nucleotides.

Proc. Natl. Acad. Sci. U. S. A. 102 , 5926-5931, (2005)

We report four-color DNA sequencing by synthesis (SBS) on a chip, using four photocleavable fluorescent nucleotide analogues (dGTP-PC-Bodipy-FL-510, dUTP-PC-R6G, dATP-PC-ROX, and dCTP-PC-Bodipy-650) (...