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Methyllucidone

Names

[ CAS No. ]:
19956-54-8

[ Name ]:
Methyllucidone

[Synonym ]:
4-Cyclopentene-1,3-dione, 4-methoxy-2-[(2E)-1-methoxy-3-phenyl-2-propen-1-ylidene]-, (2Z)-
(2Z)-4-Methoxy-2-[(2E)-1-methoxy-3-phenyl-2-propen-1-ylidene]-4-cyclopentene-1,3-dione

Biological Activity

[Description]:

Methyllucidone is a neuroprotective agent and an antioxidant that can be isolated from Lindera erythrocarpa Makino. Methyllucidone inhibits the ROS production, and activates antioxidant signaling pathways that include Nrf-2 and PI3K[1].

[Related Catalog]:

Signaling Pathways >> NF-κB >> Keap1-Nrf2
Signaling Pathways >> PI3K/Akt/mTOR >> PI3K
Research Areas >> Inflammation/Immunology

[References]

[1]. Jee-Yun Park, et al. Methyl lucidone exhibits neuroprotective effects on glutamate-induced oxidative stress in HT-22 cells via Nrf-2/HO-1 signaling. Applied Biological Chemistry volume 62, Article number: 67 (2019).

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
514.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C16H14O4

[ Molecular Weight ]:
270.280

[ Flash Point ]:
231.0±30.2 °C

[ Exact Mass ]:
270.089203

[ PSA ]:
52.60000

[ LogP ]:
2.19

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.581

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds