VU 6001966
Names
[ CAS No. ]:
2009052-76-8
[ Name ]:
VU 6001966
Biological Activity
[Description]:
A potent and selective, CNS penetrant mGlu2 negative allosteric modulator with IC50 of 78 nM; shows no inhibition for mGlu3 (IC50>30 uM); represents an exciting lead series for potential mGlu2 PET tracer development.
[References]
References 1. Bollinger KA, et al. ACS Med Chem Lett. 2017 Aug 3;8(9):919-924. View Related Products by Target mGluR
Chemical & Physical Properties
[ Molecular Formula ]:
C17H15FN4O2
[ Molecular Weight ]:
326.331