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PKI 14-22 amide, myristoylated

Names

[ CAS No. ]:
201422-03-9

[ Name ]:
PKI 14-22 amide, myristoylated

[Synonym ]:
pki 14-22 amide,cell-permeable
myristoylated protein kinase a inhibitor amide 14-22,cell-permeable
myr-grtgrrnai-nh2
pki 14-22 amide,myristoylated
protein kinase a inhibitor 14-22 amide,myristoylated

Biological Activity

[Description]:

PKI 14-22 amide,myristoylated is a potent cAMP-dependent PKA inhibitor. PKI 14-22 amide,myristoylated reduces the IgG-mediated phagocytic response and also inhibits neutrophil adhesion[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA
Signaling Pathways >> Stem Cell/Wnt >> PKA

[References]

[1]. L Ydrenius, et al. Activation of cAMP-dependent protein kinase is necessary for actin rearrangements in human neutrophils during phagocytosis. J Leukoc Biol. 2000 Apr;67(4):520-8.

Chemical & Physical Properties

[ Molecular Formula ]:
C53H100N20O12

[ Molecular Weight ]:
1209.49000

[ Exact Mass ]:
1208.78000

[ PSA ]:
554.01000

[ LogP ]:
4.40230

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds