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L-Leucine-13C6,15N

Names

[ CAS No. ]:
202406-52-8

[ Name ]:
L-Leucine-13C6,15N

[Synonym ]:
(13C6,15N)Leucine
MFCD00144625
Leucine-13C6-15N
L-Leucine-13C6,15N
L-Leucine-ul-13C,15N
L-Isoleucine-13C6,15N
13C and 15N Labeled L-leucine
SILAC Amino Acid
MFCD00144621
(S)-2-Amino-4-methylpentanoic acid-13C6,15N
(2S,3S)-2-Amino-3-methylpentanoic acid-13C6,15N
13C and 15N Labeled L-isoleucine

Biological Activity

[Description]:

L-Leucine-13C6,15N is the 13C- and 15N-labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

[Related Catalog]:

Signaling Pathways >> PI3K/Akt/mTOR >> mTOR
Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Molecular Formula ]:
13C6H1315NO2

[ Molecular Weight ]:
138.122

[ Exact Mass ]:
138.111786

[ Index of Refraction ]:
1.463

Related Compounds