MRZ 2-514
Names
[ CAS No. ]:
202808-11-5
[ Name ]:
MRZ 2-514
Biological Activity
[Description]:
MRZ 2-514 is an antagonist of the strychnine-insensitive modulatory site of the NMDA receptor (glycineB), with Ki of 33 μM.
[Related Catalog]:
[Target]
Ki: 33 μM (glycineB)[1]
[In Vitro]
MRZ 2-514 has IC50 values against peak AMPA-induced currents of 72.7 μM[1].
[In Vivo]
MRZ 2/514 has anticonvulsive action in the MES model in mice, and the effect is prolonged by probenecid[1].
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Molecular Formula ]:
C11H6BrN3O3
[ Molecular Weight ]:
308.09
[ Storage condition ]:
2-8℃