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stigmast-5-en-7-on-3§-ol

Names

[ CAS No. ]:
2034-74-4

[ Name ]:
stigmast-5-en-7-on-3§-ol

[Synonym ]:
stigmast-5-en-7-on-3§-ol
3§-hydroxystigmast-5-en-7-one
Stigmast-5-en-7-one, 3-hydroxy-, (3β)-
(3β)-3-Hydroxystigmast-5-en-7-one

Biological Activity

[Description]:

7-Ketositosterol is a phytosterol isolated from the fruits of the mulberry tree (Morus alba L.). 7-Ketositosterol can significantly inhibit Cisplatin (HY-17394)-induced apoptosis in LLC-PK1 cells and has the potential to improve Cisplatin-induced nephrotoxicity[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Lee D, et al. Identification of Renoprotective Phytosterols from Mulberry (Morus alba) Fruit against Cisplatin-Induced Cytotoxicity in LLC-PK1 Kidney Cells. Plants (Basel). 2021 Nov 17;10(11):2481.  

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
536.1±29.0 °C at 760 mmHg

[ Molecular Formula ]:
C29H48O2

[ Molecular Weight ]:
428.690

[ Flash Point ]:
226.1±16.9 °C

[ Exact Mass ]:
428.365417

[ PSA ]:
37.30000

[ LogP ]:
8.45

[ Vapour Pressure ]:
0.0±3.2 mmHg at 25°C

[ Index of Refraction ]:
1.526

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds