LSD1-IN-6

Names

[ CAS No. ]:
2035912-43-5

[ Name ]:
LSD1-IN-6

Biological Activity

[Description]:

LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> Histone Demethylase

[Target]

IC50: 123 nM (LSD1)[1]

[References]

[1]. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₃BrN₂O₃

[ Molecular Weight ]:
349.18

LSD1-IN-6

Names

Biological Activity

Chemical & Physical Properties

Related Compounds