N-t-BOC-4,4-Difluoro-L-Proline

Names

[ CAS No. ]:
203866-15-3

[ Name ]:
N-t-BOC-4,4-Difluoro-L-Proline

[Synonym ]:
4,4-Difluoro-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline
1-(tert-Butoxycarbonyl)-4,4-difluoro-L-proline
N-(tert-Butoxycarbonyl)-4,4-difluoro-L-proline
BOC-L-4,4-DIFLUOROPROLINE
MFCD03094917
(2s)-1-(tert-butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid
(S)-1-(tert-Butoxycarbonyl)-4,4-difluoro-2-pyrrolidinecarboxylic Acid
(S)-1-(tert-Butoxycarbonyl)-4,4-difluoropyrrolidine-2-carboxylic acid
N-t-BOC-4,4-Difluoro-L-Proline
N-Boc-4,4-difluoro-L-proline
1,2-Pyrrolidinedicarboxylic acid, 4,4-difluoro-, 1-(1,1-dimethylethyl) ester, (2S)-
(S)-1-Boc-4,4-difluoro-2-pyrrolidinecarboxylic Acid
1-(tert-butoxycarbonyl)-4,4-difluoropyrrolidine-(2S)-carboxylic acid
N-Boc-(2S)-4,4-difluoroproline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
340.4±42.0 °C at 760 mmHg

[ Melting Point ]:
120-124ºC

[ Molecular Formula ]:
C₁₀H₁₅F₂NO₄

[ Molecular Weight ]:
251.227

[ Flash Point ]:
159.7±27.9 °C

[ Exact Mass ]:
251.096909

[ PSA ]:
66.84000

[ LogP ]:
0.66

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.475

[ Storage condition ]:
Store at 0-5°C

MSDS

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Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%