1-(2H13)Hexanol

Names

[ CAS No. ]:
204244-84-8

[ Name ]:
1-(2H13)Hexanol

[Synonym ]:
(H)Hexan-1-ol
MFCD00144898
1-Hexan-d-ol
1-Hexan-d13-ol
n-Hexanol-d13
1-(H)Hexanol
Hexyl-d13 alcohol

Biological Activity

[Description]:

1-Hexanol-d13 is the deuterium labeled 1-Hexanol[1]. 1-Hexanol, a primary alcohol, is a surfactant that can be employed in industrial processes to enhance interfacial properties[2]. 1-Hexanol uncouples mitochondrial respiration by a non-protonophoric mechanism[3].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

[2]. Cuong V Nguyen, et al. Surface potential of 1-hexanol solution: comparison with methyl isobutyl carbinol. J Phys Chem B. 2013 Jun 27;117(25):7615-20.

[3]. M Canton, et al. The nature of uncoupling by n-hexane, 1-hexanethiol and 1-hexanol in rat liver mitochondria. Biochim Biophys Acta. 1996 May 201274(1-2):39-47.

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
158.2±3.0 °C at 760 mmHg

[ Melting Point ]:
-52ºC(lit.)

[ Molecular Formula ]:
C₆HD₁₃O

[ Molecular Weight ]:
115.255

[ Flash Point ]:
60.0±0.0 °C

[ Exact Mass ]:
115.186066

[ PSA ]:
20.23000

[ LogP ]:
1.94

[ Vapour Pressure ]:
0.9±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.416

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
28

[ RIDADR ]:
UN 2282 3/PG 3