Diallyl trisulfide

Names

[ CAS No. ]:
2050-87-5

[ Name ]:
Diallyl trisulfide

[Synonym ]:
Diallyltrisulfide
allyl trisulfide
FEMA No. 3265
diprop-2-en-1-yltrisulfane
Prop-2-enyl prop-2-enylthio disulfide
1,3-Diallyltrisulfane
Diallyl trisulfide
Diallyltrisulfane
bis-2-propenyl trisulfide
Di-2-propenyl trisulfide
diallyl trisulphide
Trisulfane, 1,3-di-2-propen-1-yl-
Trisulfide,di-2-propenyl
EINECS 218-107-8
3-(prop-2-enyltrisulfanyl)prop-1-ene
MFCD00040025
Allitridin

Biological Activity

[Description]:

Diallyl Trisulfide is isolated from Garlic. Diallyl Trisulfide suppresses the growth of Penicillium expansum (MFC99 value: ≤ 90 μg/mL) and promotes apoptosis via production of reactive oxygen species (ROS) and disintegration of cellular ultrastructure. Anticancer effect[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[Target]

Penicillium expansum (MFC99 value: ≤ 90)[1]; Apoptosis[1]; Reactive oxygen species (ROS)[1]

[References]

[1]. Pu Liu, et al. Diallyl trisulfide (DATS) effectively induced apoptosis of postharvest diseasePenicillium expansum of citrus. Annals of Microbiology. December 2009, Volume 59, Issue 4, pp 675-679.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
229.5±43.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₁₀S₃

[ Molecular Weight ]:
178.339

[ Flash Point ]:
87.8±25.2 °C

[ Exact Mass ]:
177.994461

[ PSA ]:
75.90000

[ LogP ]:
4.59

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.582

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BC6168000

CHEMICAL NAME :: Allyl trisulfide

CAS REGISTRY NUMBER :: 2050-87-5

BEILSTEIN REFERENCE NO. :: 1745734

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H10-S3

MOLECULAR WEIGHT :: 178.34

WISWESSER LINE NOTATION :: 1U2SSS2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DCTODJ Drug and Chemical Toxicology. (Marcel Dekker, 270 Madison Ave., New York, NY 10016) V.1- 1977/78- Volume(issue)/page/year: 3,249,1980

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
T+

[ RIDADR ]:
UN 2810

[ RTECS ]:
BC6168000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%