<Suppliers Price>

Propargyl-PEG8-acid

Names

[ CAS No. ]:
2055014-94-1

[ Name ]:
Propargyl-PEG8-acid

[Synonym ]:
MFCD28976699
4,7,10,13,16,19,22,25-Octaoxaoctacos-27-yn-1-oic acid

Biological Activity

[Description]:

Propargyl-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). The ADCs can be used in bacterial infections caused by Gram-negative bacteria[1].

[Related Catalog]:

Research Areas >> Cancer
Research Areas >> Infection
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Signaling Pathways >> Anti-infection >> Bacterial

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Suzanne AKERS-RODRIGUEZ, et al. Compositions and methods for the treatment of bacterial infections. WO2019126353A2.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
531.0±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H36O10

[ Molecular Weight ]:
436.494

[ Flash Point ]:
171.9±23.6 °C

[ Exact Mass ]:
436.230835

[ LogP ]:
-2.23

[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C

[ Index of Refraction ]:
1.469

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds