Pasiniazid

Names

[ CAS No. ]:
2066-89-9

[ Name ]:
Pasiniazid

[Synonym ]:
Pasiniazid
Aminosalicylic acid mixture with Isoniazid
Isonicotinsaeure-hydrazid,4-Amino-2-hydroxy-benzoat
isonicotinic acid hydrazid,4-amino-2-hydroxy benzoate
Pasiniazide
Pasiniazid [INN:DCF]
Isoniazid 4-aminosalicylate
Isonicotinsaeurehydrazid-p-aminosalicylat
Pasiniazida
Pasiniazidum

Biological Activity

[Description]:

Pasiniazid is an anti-TB and anti-leprosy drug, used to treat various types of TB and leprosy.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Related Small Molecules]

Chemical & Physical Properties

[ Boiling Point ]:
380.8ºC at 760 mmHg

[ Melting Point ]:
142-144°

[ Molecular Formula ]:
C₁₃H₁₄N₄O₄

[ Molecular Weight ]:
290.27500

[ Flash Point ]:
184.1ºC

[ Exact Mass ]:
290.10200

[ PSA ]:
151.56000

[ LogP ]:
2.03010

[ Vapour Pressure ]:
1.78E-06mmHg at 25°C

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36/37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

[Short-term effect of treatment protocol utilizing levofloxacin, pasiniazide and M. Vaccae on multi- drug resistant pulmonary tuberculosis].

Di Yi Jun Yi Da Xue Xue Bao 24(5) , 574-5, 578, (2004)

To observe the effects of the protocol combining levofloxacin, pasiniazide, M. Vaccae (V+D+M protocol) in the treatment of multi-drug resistant pulmonary tuberculosis (MDR-TB).Ninety-seven cases of MD...

[Clinical research of pasinizid on retreated sputum positive pulmonary tuberculosis in senilities].

Zhonghua Jie He He Hu Xi Za Zhi 24(10) , 608-10, (2001)

To observe and evaluate the effect and safety of pasinizid on treatment of the senile pulmonary tuberculosis with bacteriological positive.115 cases of the senile pulmonary tuberculosis with bacteriol...

A reproducible, simple, and sensitive high-performance capillary electrophoresis method for simultaneous determination of capreomycin, ofloxacin and pasiniazide in urine.

J. Pharm. Biomed. Anal. 17(4-5) , 617-22, (1998)

Separation and determination of capreomycin (Cp), ofloxacin (Oflx) and pasiniazide (Ipa) in urine by high-performance capillary electrophoresis (HPCE) with 280 nm detection have been studied systemati...