2-methylthio-N-6-isopentenyladenosine

Names

[ CAS No. ]:
20859-00-1

[ Name ]:
2-methylthio-N-6-isopentenyladenosine

[Synonym ]:
2-methylthio-N(6)-(Delta(2)-isopentenyl)adenosine
Nucleoside
2-methylthio-iPR
2-methylthio-N6-isopentenyladenosine

Biological Activity

[Description]:

2-Methylthio isopentenyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

[2]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₃N₅O₄S

[ Molecular Weight ]:
381.45

[ Exact Mass ]:
381.14700

[ PSA ]:
150.85000

[ LogP ]:
0.61080

[ Vapour Pressure ]:
1.24E-21mmHg at 25°C

2-methylthio-N-6-isopentenyladenosine

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds