NBD-14107
Names
[ CAS No. ]:
2086328-94-9
[ Name ]:
NBD-14107
Biological Activity
[Description]:
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; exhibits antiviral activity against a large panel of HIV-1 Env-pseudotyped viruses representing diverse subtypes of clinical isolates with mean EC50 of 0.49 uM; also inhibits HIV-1 RT with IC50 of 8.4 uM; exhibits improving the potency, toxicity, and ADMET profile compared with NBD-14010. HIV Preclinical
[References]
References 1. Curreli F, et al. J Med Chem. 2017 Apr 13;60(7):3124-3153. View Related Products by Target HIV HIV
Chemical & Physical Properties
[ Molecular Formula ]:
C17H15ClF2N4O2S
[ Molecular Weight ]:
412.84