SR 16832

Names

[ CAS No. ]:
2088135-12-8

[ Name ]:
SR 16832

[Synonym ]:
2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide
Benzamide, 2-chloro-N-(6-methoxy-4-quinolinyl)-5-nitro-

Biological Activity

[Description]:

SR 16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone; a useful, complementary chemical tools for researchers to use to simultaneously inhibit both orthosteric and allosteric ligand-induced cellular activation of PPARγ.

[References]

References 1. Brust R, et al. ACS Chem Biol. 2017 Apr 21;12(4):969-978. View Related Products by Target PPAR

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
492.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₂ClN₃O₄

[ Molecular Weight ]:
357.748

[ Flash Point ]:
251.5±28.7 °C

[ Exact Mass ]:
357.051636

[ LogP ]:
3.70

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.708

SR 16832

Names

Biological Activity

Chemical & Physical Properties

Related Compounds