Thalidomide-NH-(CH2)3-NH-Boc
Names
[ CAS No. ]:
2093386-36-6
[ Name ]:
Thalidomide-NH-(CH2)3-NH-Boc
Biological Activity
[Description]:
Thalidomide-NH-(CH2)3-NH-Boc is a Boc-modified Thalidomide (HY-14658), which acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)3-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)3-NH-Boc is a key intermediate in the synthesis of CRBN-based designed PROTAC molecules targeting 11β-substituted estradiol.
[Related Catalog]:
Chemical & Physical Properties
[ Molecular Formula ]:
C21H26N4O6
[ Molecular Weight ]:
430.45