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Thalidomide-NH-C6-NH2

Names

[ CAS No. ]:
2093386-50-4

[ Name ]:
Thalidomide-NH-C6-NH2

Biological Activity

[Description]:

E3 Ligase Ligand-Linker Conjugate is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H24N4O4

[ Molecular Weight ]:
372.42

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds