4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylpropyl)-2-thioxo-
Names
[ CAS No. ]:
2095-57-0
[ Name ]:
4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylpropyl)-2-thioxo-
[Synonym ]:
5-ethyl-5-sec-butyl-2-thio-barbituric acid
5-sec-Butyl-5-ethyl-2-thiobarbituric acid
thiobutobarbitone,Inactin
4,6(1H,5H)-Pyrimidinedione,5-ethyldihydro-5-(1-methylpropyl)-2-thioxo
5-Aethyl-5-sec-butyl-2-thio-barbitursaeure
5-sec-butyl-5-ethyl-2-thioxo-dihydro-pyrimidine-4,6-dione
5-ethyl-5-(1-methylpropyl)-2-thiobarbituric acid
thiobutabarbital
5-(sec-Butyl)-5-ethyldihydro-2-thioxopyrimidine-4,6(1H,5H)-dione
BARBITURIC ACID,5-sec-BUTYL-5-ETHYL-2-THIO
Chemical & Physical Properties
[ Density]:
1.19g/cm3
[ Melting Point ]:
163-164ºC
[ Molecular Formula ]:
C10H16N2O2S
[ Molecular Weight ]:
228.31100
[ Exact Mass ]:
228.09300
[ PSA ]:
93.78000
[ LogP ]:
1.56450
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CQ2278000
- CHEMICAL NAME :
- Barbituric acid, 5-sec-butyl-5-ethyl-2-thio-
- CAS REGISTRY NUMBER :
- 2095-57-0
- BEILSTEIN REFERENCE NO. :
- 0199128
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C10-H16-N2-O2-S
- MOLECULAR WEIGHT :
- 228.34
- WISWESSER LINE NOTATION :
- T6VMYMV FHJ CUS FY2&1 F2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 103 mg/kg
- TOXIC EFFECTS :
- Behavioral - antipsychotic
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 132,164,1961
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 57,1961,1935
Safety Information
[ WGK Germany ]:
3
[ RTECS ]:
CQ2278000
[ HS Code ]:
2933599090
Synthetic Route
Customs
[ HS Code ]: 2933599090
[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%