PROTAC IAP binding moiety 3

Names

[ CAS No. ]:
2095244-43-0

[ Name ]:
PROTAC IAP binding moiety 3

Biological Activity

[Description]:

PROTAC IAP binding moiety 3, the LCL161 derivative (IAP ligand) moiety, binds to ABL inhibitor via a linker to form SNIPER[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H36N4O4S

[ Molecular Weight ]:
512.66

Related Compounds