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MV-1-NH-Me

Names

[ CAS No. ]:
2095244-62-3

[ Name ]:
MV-1-NH-Me

Biological Activity

[Description]:

PROTAC IAP binding moiety 2, the MV-1 (IAP ligand) moiety, binds to ABL inhibitor via a linker to form SNIPER[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₃H₄₅N₅O₄

[ Molecular Weight ]:
575.74