PZ-1361

Names

[ CAS No. ]:
2095849-69-5

[ Name ]:
PZ-1361

Biological Activity

[Description]:

PZ-1361 is a potent and selective 5-HT7 receptor antagonist with Ki of 33 nM, exhibit significant in vivo antidepressant and pro-cognitive properties in rodents.

[References]

1. Vittorio Canale, et al. J Org Chem. 2020 Aug 21;85(16):10958-10965.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₂₉ClN₂O₄S

[ Molecular Weight ]:
501.038

Related Compounds

PZ-II-029
PZ-128
Pz-Pro-Leu-Gly-Pro-D-Arg-OH trifluoroacetate salt
Pz-1
PZ-601
Pz-Pro-Leu-OH
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine
4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine