Decanoyl-RVKR-CMK TFA
Names
[ CAS No. ]:
2098497-25-5
[ Name ]:
Decanoyl-RVKR-CMK TFA
Biological Activity
[Description]:
Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits over-expressed gp160 processing and HIV-1 replication[1].
[Related Catalog]:
[In Vitro]
Decanoyl-RVKR-CMK (DecRVKRcmk) TFA inhibits HIV-2ROD replication by blocking envelope glycoprotein precursor processing in the Jurkat lymphocyte cell[1]. Decanoyl-RVKR-CMK (DecRVKRcmk) TFA blocks regulated secretion of VGF[2]. Cell Viability Assay[1] Cell Line: HeLaCD4 cells infected with recombinant vaccinia viruses at a multiplicity of infection (MOI) of 5 PFU/mL Concentration: 35 and 70 µΜ Incubation Time: 7 days Result: Peptide at 35 µM significantly inhibited ex vivo HIV-1 and HIV-2 replications (70-80% inhibition).
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C36H67ClF3N11O7
[ Molecular Weight ]:
858.43