Glycine-13C2,15N

Names

[ Name ]:
Glycine-13C2,15N

[Synonym ]:
13C and 15N Labeled glycine Aminoacetic acid-13C2,15N Aminoethanoic acid-13C2,15N
Glycine-13C2,15N
Aminoethanoic Acid-13C2,15N
(C,N)Glycine
Glycine-C-N
Glycosthene-13C2,15N
Aciport-13C2,15N
Glycocoll-13C2,15N
Glycolixir-13C2,15N
Padil-13C2,15N
Gyn-Hydralin-13C2,15N
Glicoamin-13C2,15N

Biological Activity

[Description]:

Glycine-13C2,15N is the 13C- and 15N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR

Research Areas >> Neurological Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
240ºC (dec.)(lit.)

[ Molecular Formula ]:
₁₃C₂H₅₁₅NO₂

[ Molecular Weight ]:
78.045

[ Exact Mass ]:
78.035774

[ PSA ]:
63.32000

[ Index of Refraction ]:
1.461

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport