m-PEG10-Tos

Names

[ CAS No. ]:
211859-75-5

[ Name ]:
m-PEG10-Tos

Biological Activity

[Description]:

m-PEG10-Tos is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Jennifer Riggs-Sauthier, et al. Oligomer-opioid agonist conjugates. US8575196B2.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₄₆O₁₂S

[ Molecular Weight ]:
582.7

[ Storage condition ]:
2-8°C

m-PEG10-Tos

Names

Biological Activity

Chemical & Physical Properties

Related Compounds