VU 6010572
Names
[ CAS No. ]:
2126784-39-0
[ Name ]:
VU 6010572
Biological Activity
[Description]:
A potent and selective, CNS penetrant mGlu3 negative allosteric modulator with IC50 of 245 nM; show no inhibition for mGlu2 (IC50>30 uM); displays improved physiochemical properties and in vivo efficacy in a mouse tail suspension test (MED = 3 mg/kg i.p.).
[References]
References 1. Engers JL, et al. ACS Med Chem Lett. 2017 Aug 15;8(9):925-930. View Related Products by Target mGluR
Chemical & Physical Properties
[ Molecular Formula ]:
C20H18FNO3
[ Molecular Weight ]:
339.366