2,2'-dithiobis(5-nitropyridine)
Names
[ CAS No. ]:
2127-10-8
[ Name ]:
2,2'-dithiobis(5-nitropyridine)
[Synonym ]:
Bis(5-nitro-2-pyridyl) disulfide,DTNP
MFCD00006453
DTNP
1,2-bis(5-nitropyridin-2-yl)disulfane
2,2'-DIMETHYL-4,4'-BIPHENYLDIOL
Bis(5-nitro-2-pyridyl) disulfide
5,5'-dinitro-2,2'-dithiodipyridine
EINECS 218-344-7
bis(5-nitro-pyridin-2-yl)-disulfide
2,2'-Dithiobis(5-nitropyridine)
5-nitro-pyridin-2-yl disulphide
Chemical & Physical Properties
[ Density]:
1.65g/cm3
[ Boiling Point ]:
514.2ºC at 760mmHg
[ Melting Point ]:
155-157 °C(lit.)
[ Molecular Formula ]:
C10H6N4O4S2
[ Molecular Weight ]:
310.30900
[ Flash Point ]:
264.8ºC
[ Exact Mass ]:
309.98300
[ PSA ]:
168.02000
[ LogP ]:
4.13880
[ Vapour Pressure ]:
3.58E-10mmHg at 25°C
[ Index of Refraction ]:
1.733
[ Storage condition ]:
Store at RT.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UT2964000
- CHEMICAL NAME :
- Pyridine, 2,2'-dithiobis(5-nitro-
- CAS REGISTRY NUMBER :
- 2127-10-8
- BEILSTEIN REFERENCE NO. :
- 0305413
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H6-N4-O4-S2
- MOLECULAR WEIGHT :
- 310.32
- WISWESSER LINE NOTATION :
- T6NJ ENW BSS- BT6NJ ENW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 50 ug/plate
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 67,123,1979
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
S36/37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UT2964000
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Pflugers Arch. 467 , 2423-35, (2015)
SCN11A encodes the voltage-gated sodium channel NaV1.9, which deviates most strongly from the other eight NaV channels expressed in mammals. It is characterized by resistance to the prototypic NaV cha...
Disinactivation of N-type inactivation of voltage-gated K channels by an erbstatin analogue.J. Biol. Chem. 279(28) , 29226-30, (2004)
In some A-type voltage-gated K channels, rapid inactivation is achieved through the binding of an N-terminal domain of the pore-forming alpha-subunit or an associated beta-subunit to a cytoplasmic acc...
2,2'-Dithiobis(5-nitropyridine) (DTNP) as an effective and gentle deprotectant for common cysteine protecting groups.J. Pept. Sci. 18(1) , 1-9, (2012)
Of all the commercially available amino acid derivatives for solid phase peptide synthesis, none has a greater abundance of side-chain protection diversity than cysteine. The high reactivity of the cy...