BCL6 inhibitor 8c
Names
[ CAS No. ]:
2130878-25-8
[ Name ]:
BCL6 inhibitor 8c
Biological Activity
[Description]:
A novel potent, in vivo-active BCL6 inhibitor with IC50 of 0.1 uM in ELISA assays; exhibits good cellular BCL6BTB/ BCoR PPI inhibitory activity in the submicromolar range (M2H IC50=0.72 uM), showed a good pharmacokinetic profile, which is acceptable for both in vitro and in vivo studies.
[References]
References 1. Yasui T, et al. Bioorg Med Chem. 2017 Sep 1;25(17):4876-4886. View Related Products by Target Bcl-2
Chemical & Physical Properties
[ Molecular Formula ]:
C20H20ClN3O5
[ Molecular Weight ]:
417.846
Safety Information
[ Hazard Codes ]:
Xi