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AST2818 mesylate

Names

[ CAS No. ]:
2130958-55-1

[ Name ]:
AST2818 mesylate

Biological Activity

[Description]:

AST2818 mesylate is an EGFR inhibitor.

[Related Catalog]:

Research Areas >> Cancer

[Target]

EGFR


[In Vitro]

AST2818 mesylate is designed to inhibit EGFR active mutations as well as the T790M acquired resistant mutation[1].

[References]

[1]. Y.Shi, et al. P2.03-028 Third Generation EGFR Inhibitor AST2818 (Alflutinib) in NSCLC Patients with EGFR T790M Mutation: A phase1/2 Multi-Center Clinical Trial. J Thorac Oncol. 2017 Nov, 12(11): S2138.


[Related Small Molecules]

Osimertinib (AZD9291) | Tyrphostin B42 (AG-490) | Neratinib (HKI-272) | Genistein | (-)-Epigallocatechin gallate | AG-1478 | Dacomitinib (PF-00299804) | Irbinitinib | Poziotinib | Olmutinib | Sapitinib | AZD-3759 | Pyrotinib | Canertinib dihydrochloride | BMS-690514

Chemical & Physical Properties

[ Molecular Formula ]:
C29H35F3N8O5S

[ Molecular Weight ]:
664.7

[ Storage condition ]:
2-8℃

Related Compounds