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CDK4/6-IN-4

Names

[ CAS No. ]:
2138499-06-4

[ Name ]:
CDK4/6-IN-4

Biological Activity

[Description]:

CDK4/6-IN-4, the active metabolite of Abemaciclib, is a selective CDK4/6 inhibitor for the treatment of cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> CDK

[Target]

CDK4

CDK6


[References]

[1]. Richard Paul Beckmann, et al. Combination therapy with notch and cdk4/6 inhibitors for the treatment of cancer. WO2017180389A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H32F2N8O

[ Molecular Weight ]:
522.59

Related Compounds