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Olaparib D5

Names

[ CAS No. ]:
2143107-56-4

[ Name ]:
Olaparib D5

Biological Activity

[Description]:

Olaparib D5 (AZD2281 D5) is a deuterium labeled Olaparib. Olaparib is a potent and oral PARP inhibitor[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Epigenetics >> PARP

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> Autophagy >> Mitophagy

Signaling Pathways >> Cell Cycle/DNA Damage >> PARP

[References]

[1]. Menear KA, et al. 4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1. J Med Chem. 2008 Oct 23;51(20):6581-91.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₁₈D₅FN₄O₃

[ Molecular Weight ]:
439.49

Related Compounds