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DBCO-PEG5-NHS ester

Names

[ CAS No. ]:
2144395-59-3

[ Name ]:
DBCO-PEG5-NHS ester

Biological Activity

[Description]:

DBCO-PEG4-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Craig L. Duvall, et al. Conjugation of lipophilic albumin-binding moiety to rna for improved carrier-free in vivo pharmacokinetics and gene silencing. US20180064749A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C36H43N3O11

[ Molecular Weight ]:
693.74

[ Storage condition ]:
-20°C

Related Compounds