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Phe-Lys(Fmoc)-PAB

Names

[ CAS No. ]:
2149584-03-0

[ Name ]:
Phe-Lys(Fmoc)-PAB

Biological Activity

[Description]:

Phe-Lys(Fmoc)-PAB is a cathepsin cleavable ADC linker used for the antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Others

[Target]

Cleavable


[References]

[1]. Abu Ajaj K, et al. Development of protein-binding bifunctional linkers for a new generation of dual-actingprodrugs. Bioconjug Chem. 2009 Feb;20(2):390-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C37H40N4O5

[ Molecular Weight ]:
620.74

[ Storage condition ]:
-20°C

Related Compounds