YKL-06-061

Names

[ Name ]:
YKL-06-061

[Synonym ]:
YKL 06-061

Biological Activity

[Description]:

YKL-06-061 is a potent, selective, second-generation salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> Salt-inducible Kinase (SIK)

[Target]

IC50: 6.56 nM/1.77 nM/20.5 nM (SIK1/2/3)[1].

[References]

[1]. Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₃₇N₇O₂

[ Molecular Weight ]:
527.3

YKL-06-061

Names

Biological Activity

Chemical & Physical Properties

Related Compounds