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Propargyl-PEG8-NHS ester

Names

[ CAS No. ]:
2182601-74-5

[ Name ]:
Propargyl-PEG8-NHS ester

[Synonym ]:
MFCD31536764

Biological Activity

[Description]:

Propargyl-PEG8-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Satwik Kamtekar, et al. Modified biotin-binding proteins for immobilization. WO2019126734A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H39NO12

[ Molecular Weight ]:
533.57

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds