5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE

Names

[ Name ]:
5-AMINO-2-(4-TERT-BUTYLPHENOXY)PYRIDINE

[Synonym ]:
5-Amino-2-(4-tert-butylphenoxy)pyridine
6-(4-(tert-Butyl)phenoxy)pyridin-3-amine
MFCD00052647

Biological Activity

[Description]:

CB-103 is a notch signaling pathway inhibitor extracted from patent US9296682B2. CB-103 is developed for the treatment of cancers[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Stem Cell/Wnt >> Notch

[References]

[1]. Freddy Radtke, et al. Inhibitors of notch signalling pathway and use thereof in treatment of cancers. US9296682B2.

Chemical & Physical Properties

[ Density]:
1.09g/cm3

[ Boiling Point ]:
394.2ºC at 760mmHg

[ Melting Point ]:
89-90ºC

[ Molecular Formula ]:
C₁₅H₁₈N₂O

[ Molecular Weight ]:
242.31600

[ Flash Point ]:
192.2ºC

[ Exact Mass ]:
242.14200

[ PSA ]:
48.14000

[ LogP ]:
4.33480

[ Vapour Pressure ]:
2.01E-06mmHg at 25°C

[ Index of Refraction ]:
1.574

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%