VPC-13566

Names

[ Name ]:
VPC-13566

Biological Activity

[Description]:

VPC-13566 is an advanced BF3-specific small molecule that was previously reported to effectively inhibit AR transcriptional activity and to displace the BAG1L peptide from the BF3 pocket. VPC-13566 inhibits the growth of various prostate cancer cell lines, including an enzalutamide-resistant cell line, and reduces the growth of AR-dependent prostate cancer xenograft tumors in mice.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₄N₂

[ Molecular Weight ]:
258.32

Related Compounds

VPC-70619
VPC-18005
VPC-80051(VPC80051)
VPC-13789
VPC-18005
VPC-14228
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
3-[1-(2-methylpropyl)-1H-pyrazol-5-yl]butanoic acid
(4-Methyl-tetrahydro-furan-2-yl)-methanol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
1-(3-Fluoro-2-methoxyphenyl)cyclohexan-1-amine
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
tert-Butyl-DL-alanine